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Kaplan Q-Bank for NBDE Part 1 2021 PDF is one of the best book for quick review. It is very good book to study a a day before your exam. It can also cover your viva questions and will help you to score very high.
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Examples from the Q-Bank
- At which of the following ages does fetal movement first occur?
- 1 month
- 2 months
- 4 months
- 6 months
- 7 months
The correct answer is B. Neuromuscular development is sufficient to allow fetal movement in the eighth week of life. Other features of Week 8 include the first appearance of a thin skin, a head as large as the rest of the body, forward-looking eyes, the appearance of digits on the hands and feet, appearance of testes and ovaries (but not distinguishable external genitalia), and a crown-rump length of approximately 30 mm. By the end of the eighth week, nearly all adult structures have at least begun to develop, and the fetus “looks like a baby.”
- Most of the oocytes in the ovary of a prepubescent girl are in which meiotic stage?
- Anaphase of the second meiotic division
- Metaphase of the first meiotic division
- Metaphase of the second meiotic division
- Prophase of the first meiotic division
- Telophase of the first meiotic division
The correct answer is D. The first meiotic division is the “reduction” meiotic division, in which the diploid complement of DNA is reduced to a haploid complement. The bulk of oocytes in premenopausal women, girls, and babies are arrested at prophase of the first meiotic division.
Postmenopausal women have very few viable oocytes. It is important to note that ovulation occurs before the oocyte is completely mature. The secondary oocyte leaving the follicle is in metaphase of the second meiotic division (choice C). The cell’s metabolic operations have been discontinued and the oocyte drifts in a state of “suspended animation,” awaiting the necessary stimulus for further development. If fertilization does not occur, the oocyte disintegrates without completing meiosis.
- An abrasion results in the total loss of epidermis over a large area of an arm, but one month later, the abrasion has healed, with regrowth of the epidermis. Which of the following mechanisms accounts for the restoration of the epidermis over the abraded area?
- The growth of epidermis from hair follicles and sweat glands in the dermis
- Migration of endothelial cells from newly grown capillaries
- Transformation of dermal fibroblasts into epidermal cells
- Transformation of macrophages into epidermal cells
- Transformation of melanocytes into epidermal cells
The correct answer is A. The dermis contains skin appendages (e.g., hair follicles), which contain epithelial stem cells. In the process of healing a large area where the epidermis has been lost but the dermis is intact, re-epithelialization occurs by growth of epidermal cells from the underlying skin appendages, as well as from the intact epidermis along the wound edges. Physiologically, the dermis lies beneath the epidermis. It has two major components, a superficial papillary layer, and a deeper reticular layer. The papillary layer contains the capillaries and the sensory neurons, which supply the surface of the skin. The reticular layer consists of an interwoven meshwork of dense irregular connective tissue.
None of the other cell types are known to directly contribute to the regeneration of epidermis over the abraded skin.
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