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Learn Now: Advances in Molecular Diagnostics

In Molecular Diagnostics: Cancer Diagnosis and Patient Management, experts in the field review current concepts and up-to-date techniques, delving into the appropriate use of molecular assays for different tumor types to inform diagnosis, prognosis, or treatment using evidence-based guidelines.

Lectures in this online CME course illustrate common diagnostic pitfalls, with additional focus on variant interpretation and the complexity of billing for molecular tests. It’s continuing medical education that will help you to:

• Develop appropriate tissue-handling protocols
• Evaluate cytogenetic and molecular techniques, including next generation sequencing assays
• Recognize cost-effective, time-sensitive approaches to molecular studies, including cell free DNA testing
• Determine the process of clinical interpretation of genetic variation
• Analyze costs and potential sources of revenue for molecular diagnostics programs
• Consider essential and emerging biomarkers in common adult and pediatric solid and liquid tumors

An Introduction to Molecular Diagnostics – Fei Dong, MD

Specimen Handling for Molecular Success – Lynette M. Sholl, MD

An Introduction to Cytogenetic Techniques – Azra Ligon, PhD

Question and Answer Session – Moderator – Valentina Nardi, MD; Drs. Dong, Sholl, and Ligon

An Introduction to Next Generation Sequencing – Laura MacConaill, PhD

An Introduction to Bioinformatic Pipelines for NGS – Ryan J. Schmidt, MD, PhD

Question and Answer Session – Moderator – Valentina Nardi, MD; Drs. MacConaill and Schmidt

An Introduction to Liquid Biopsy (Cell Free DNA Sequencing) – Technical Topics – Long Phi Le, MD, PhD

An Introduction to Liquid Biopsy (Cell Free DNA Sequencing) – Clinical Applications – Giulia Siravegna, PhD

Tumor Mutation Burden and Microsatellite Instability Testing – Jonathan Nowak, MD, PhD

Question and Answer Session – Moderator – Valentina Nardi, MD; Drs. Le, and Nowak

Live Advanced Workshop: Informatics – Long Phi Le, MD, PhD

Molecular Diagnostics for Breast Cancer – Deborah Dillon, MD

Molecular Diagnostics of Gynecologic Tumors – Lauren Ritterhouse, MD, PhD

Question and Answer Session – Moderator – Lynette M. Sholl, MD; Drs. Dillon and Ritterhouse

Molecular Diagnostics of Melanoma – Ryan J. Sullivan, MD

Molecular Diagnostics of Pediatric and Rare Tumors – Valentina Nardi, MD

Metastatic Inflammatory Myofibroblastic Tumor – Alanna Church, MD and Katherine Janeway, MD, MMSc

Question and Answer Session – Moderator – Lynette M. Sholl, MD; Drs. Church, Janeway and Sullivan

Clinical Interpretation of Sequence and Copy Number Variants (Cancer NGS) – Fei Dong, MD

Clinical Interpretation for Gene Fusions – Valentina Nardi, MD

Clinical Interpretation of Germline Cancer Predisposition – Diana Mandelker, MD, PhD

Question and Answer Session – Moderator – Lynette M. Sholl, MD; Drs. Dong, Mandelker, and Nardi

Live Advanced Workshop: Fusion Interpretation – Adam Fisch, MD, PhD

Hot Topics in Myeloid Neoplasms – Valentina Nardi, MD

Hot Topics in Measurable (Minimal) Residual Disease Testing – Annette S. Kim, MD, PhD

Targetable Fusions in Acute Lymphoblastic Leukemia – Marian H. Harris, MD, PhD

Question and Answer Session – Moderator – Lynette M. Sholl, MD; Drs. Harris, Nardi and Kim

Molecular Diagnostics for B-cell Lymphomas – Scott B. Lovitch, MD, PhD

Molecular Diagnostics for T-cell Lymphomas – David Weinstock, MD

Hematological Malignancy Case Presentation – Hanno Hock, MD, PhD and Valentina Nardi, MD

Question and Answer Session – Moderator – Lynette M. Sholl, MD; Drs. Lovitch, Nardi, Weinstock, and Hock

Molecular Diagnostics for Sarcomas – Adrian Marino-Enriquez, MD, PhD

Molecular Diagnostics for Gliomas – David Meredith, MD, PhD

Clinical Applications of Whole Genome DNA Methylation Profiling – Matija Snuderl, MD

Question and Answer Session – Moderator – Valentina Nardi, MD; Drs. Marino-Enriquez, Meredith, and Snuderl

Advanced Workshop: Copy Number by Microarray & NGS – Adrian Dubuc, PhD

Molecular Diagnostics for Lung Cancer – Lynette M. Sholl, MD

Molecular Diagnostics for Thyroid Cancer – Dora Dias-Santagata, PhD, FACMG

Question and Answer Session – Moderator – Valentina Nardi, MD; Drs. Dias-Santagata and Sholl

Molecular Biomarkers for GU Cancers – Atish Choudhury, MD, PhD

Molecular Diagnostics for GI Cancers – Jonathan Nowak, MD, PhD

Clinical Case Presentation and Discussion (Lung Tumor) – Mark M. Awad, MD, PhD and Lynette M. Sholl, MD

Question and Answer Session – Moderator – Valentina Nardi, MD; Drs. Awad, Sholl, Choudhury, and Nowak

Billing and Regulatory Issues – Jochen K. Lennerz, MD, PhD

Opportunities in Molecular Lab Management – Neal Lindeman, MD

Clinical Trials and Regulatory Affairs – Hetal Marble, PhD

Question and Answer Session – Moderator – Valentina Nardi, MD; Drs. Iafrate, Lennerz, Lindeman, and Marble