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From bioinformatics to nanotechnology, advances in basic research ultimately drive advances in clinical care. This book provides a comprehensive summary of all current research methodologies for transnational and pre-clinical studies in biomechanics and orthopedic trauma surgery. With this “roadmap” at hand, specialists and trainees will have the tools to conduct high-quality experimental research in any area of musculoskeletal science, with a solid understanding of how the findings can be applied in patient care. In this blog post, you will be able to download free PDF e-book copy of Experimental Research Methods in Orthopedics and Trauma PDF.

Table of Contents

Features of Experimental Research Methods in Orthopedics and Trauma PDF

Here are important features of this book:

Utilizes the principles and methodology of modern, evidence-based medicine in pre-clinical musculoskeletal research
Offers a comprehensive analysis of in vivo models for
studying different components of the musculoskeletal system
Demonstrates how principles of structural, functional, and numerical biomechanics can be utilized in well-defined experimental research studies – spanning topics from fracture fixation to gait analysis to bone remodeling
Covers the role of new macroscopic CT and ultrasound imaging techniques for assessing bone and cartilage function
Explores cutting-edge developments in cell culture research, molecular testing, and tissue engineering
Provides practical advice, a glossary of key terminology, and hundreds of illustrations to familiarize clinicians with every aspect of designing and interpreting an effective research study

With 54 state-of-the-art chapters by orthopedic surgeons, musculoskeletal physicians, biologists, engineers, physicists, and mathematicians, Experimental Research Methods in Orthopedics and Trauma is the
authoritative reference on the topic. It is essential for clinicians, basic researchers, and orthopedic surgical trainees who need to understand experimental research methodology, apply its findings, and participate fully in research activities.

Below is the complete table of contents presented in Experimental Research Methods in Orthopedics and Trauma PDF:

Part 1 Why Do We Need Experimental Research?

1 Evidence-Based Research
2 Establishing a Basic Research Facility in Orthopedic Surgery
3 Good Laboratory Practice and Quality Control
4 How to Prepare for a Period in Research

Part 2 Structural Biomechanics

5 Physiological Boundary Conditions for Mechanical Testing
6 Static, Dynamic, and Fatigue Mechanical Testing
7 Use of Human and Animal Specimens in Biomechanical Testing
8 Whole Bone Biomechanics
9 Biomechanics of Trabecular and Cortical Bone
10 Biomechanics of Fracture Fixation
11 Biomechanical Assessment of Fracture Repair
12 Biomechanics of Cartilage
13 Biomechanics of Joints
14 Spine Biomechanics

Part 3 Functional Biomechanics

15 Musculokeletal Dynamics
16 Measurement Techniques
17 Clinical Assessment of Function
18 Functional Biomechanics with Cadaver Specimens

Part 4 Numerical Biomechanics

19 Inverse Dynamics
20 Principles of Finite Elements Analysis
21 Validation of Finite Element Models
22 Computational Biomechanics of Bone
23 Numerical Simulation of Implants and Prosthetic Devices
24 Numerical Simulation of Fracture Healing and Bone Remodelling

Part 5 Imaging

25 Micro-Computed Tomography Imaging of Bone Tissue
26 Imaging Bone
27 Ultrasound Techniques for Imaging Bone
28 In Vivo Scanning
29 Imaging of Cartilage Function
30 Histochemistry Bone and Cartilage
31 Immunohistochemistry
32 Molecular Imaging In Situ Hybridization
33 Laser Scanning Confocal Microscopy and Laser Microdissection
34 Image Analysis Histomorphometry Stereology

Part 6 Cellular Studies

35 Cell Culture Research
36 Cartilage Explants and Organ Culture Models
37 Fluid Flow and Strain in Bone
38 Biomechanics of Bone Cells

Part 7 Molecular Techniques in Bone Repair

39 Molecular Testing
40 Genetically Modified Models for Bone Repair

Part 8 In Vivo Models

41 General Considerations for an In Vivo Model
42 Animal Models for Bone Healing
43 Models for Impaired Healing
44 In Vivo Models for Bone and Joint Infections
45 In Vivo Models for Articular Cartilage Repair
46 In Vivo Soft Tissue Models

Part 9 Tissue Engineering

47 Scaffolds for Tissue Engineering and Materials for Repair
48 Use of Growth Factors in Musculoskeletal Research
49 Stem Cells for Musculoskeletal Repair
50 Biological Evaluation and Testing of Medical Devices

Part 10 Statistics for Experimental Research

51 Study Design
52 Power and Sample Size Calculation
53 Nonparametric versus Parametric Tests
54 How to Limit Bias in Experimental Research

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Product Details

Below are the technical specifications of Experimental Research Methods in Orthopedics and Trauma PDF.

Book Name : Experimental Research Methods in Orthopedics and Trauma
Edition : 1st Edition | | ISBN : 3131731117
Author Name : Peter Augat; Hamish Simpson;
Category : Medical
Format / Pages : PDF – 464 Pages

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