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The burgeoning field of Genetics is a complex and formidable topic for the student and practitioner. It is easy to get lost in the forest for the trees since genetics lends itself anywhere from a basic foundation of DNA and its parts, to a more complicated and nuanced understanding of how these parts work together, what happens when things go wrong, how to diagnose and treat genetic disorders, and the latest advances and areas of hope in genetic research.
Clinical Genetics Made Ridiculously Simple presents a way to rapidly visualize the field as a whole, including basic genetics, chromosomal abnormalities, epigenetic disorders, cancer, screening tests, gene sequencing, CRISPR, homeobox genes, and changing approaches to the clinical diagnosis and treatment of genetic conditions.
The author builds from the basics of genetics and DNA, to an understanding of how our genetic material functions, what we presently know about genetic defects, and cutting edge solutions to these problems. Each topic is carefully taught, one step at a time, so that the student is never lost, all in 112 pages!
Table of Contents
Book Details
Pages
112
ISBN
9781935660439
Publication
September 15, 2020
Language
English
About The Author
Stephen Goldberg
Stephen Goldberg, MD, a graduate of the Albert Einstein College of Medicine, trained in Neurology, Ophthalmology, and Family Medicine. He is a neurologic researcher, teacher, computer programmer, writer, editor, and president of the Medmaster publishing company. Dr. Goldberg has published numerous papers on neuronal development and regeneration through research at the Albert Einstein College of Medicine, National Institutes of Health, New York Medical College and the University of Miami. He is the author of the best-selling book, Clinical Neuroanatomy Made Ridiculously Simple, as well as the interactive computer program Neurologic Localization. As a coordinator of neuroanatomy education at the University of Miami Miller School of Medicine for 25 years, his reputation is that of an educator who can simplify complex topics. He received the George Paff Most Outstanding Professor Teaching Award 11 times at the U of M and was invited to be the keynote speaker at the medical school graduation commencement at the Washington University School of Medicine in St. Louis in 2004. He has also authored textbooks of Anatomy, Physiology, Biochemistry, Biostatistics, Neurology, Ophthalmology and Computer Programming, as well as many interactive computer programs on a variety of medical topics.
Table of Contents:
Introduction
Part I. Classic Genetics
Chapter 1. Mendelian Genetics What Exactly Is a Gene?
Nomenclature
Chapter 2. Mitosis and Meiosis Mitosis
Meiosis
Chapter 3. DNA Replication, Transcription, and Translation Replication of DNA -Transposons -Tandem Repeats Transcription of DNA into RNA -Introns -Transcription Factors Translation of RNA into Proteins -Messenger, Transfer, and Ribosomal RNA -Protein Modification -Mitochondrial Inheritance
Part II. When Things Go Wrong
Chapter 4. Chromosomal Abnormalities Too Many or Too Few Chromosomes
Translocation of Chromosome Segments
Inversion of Chromosome Segments
Duplications and Deletions of Chromosome Segments
DNA Point Mutations
Chapter 5. Epigenetic Disorders
Chapter 6. Cancer Inherited Cancer
Part III. Diagnosis and Treatment of Genetic Disorders
Chapter 7. History and Physical Exam Pedigree Tree
Chapter 8. Laboratory Should You Do Genetic Testing?
Indications for Referral and Cytogenetic Testing
Cytogenetic Screening Tests
Polymerase Chain Reaction (PCR)
Fluorescence In Situ Hybridization (FISH)
Next Generation Sequencing
Chapter 9. Treatment CRISPR
Treatment of Cancer -Immunotherapy Pharmacogenomics
Chapter 10. Homeobox Genes Appendix. Diseases Index
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