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Overview
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Features of Oxford Textbook of Medicine 6th Edition Volume 1 PDF
Following are the features of Oxford Textbook of Medicine 6th Edition Volume 1 PDF:
The go-to textbook in general medicine
The very best in international medicine from over 900 of the world’s greatest clinicians and medical scientists
Unparalleled integration of basic science and clinical practice, covering all areas of internal medicine in detail
The most comprehensive coverage of infectious diseases to be found in any textbook of medicine
An ideal resource for anyone wanting to quickly refresh their knowledge of areas outside their specialism
Recognised around the world as the trusted and ultimate reference to the whole of medicine.
New to this Edition:
Purchasers of the sixth edition get FREE access to the content on Oxford Medicine Online for the life of the edition, including future updates.
A new foreword by Professor Sir John Bell.
259 videos, many of them brand new.
96 brand new chapters and over 2000 more pages.
The Oxford Textbook of Medicine is the foremost international textbook of medicine. Unrivalled in its coverage of the scientific aspects and clinical practice of internal medicine and its subspecialties, it is a fixture in the offices and wards of physicians around the world, as well as being a key resource for medico-legal practitioners. Accessible digitally with regular updates, as well as in print, readers are provided with multiple avenues of access depending on their need and preference.
More comprehensive, more authoritative, and more international than any other textbook; Oxford Textbook of Medicine focuses on offering both perspective and practical guidance on clinical management and prevention of disease.
Introductory sections focus on the patient experience, medical ethics and clinical decision making, outlining a philosophy which has always characterized the Oxford Textbook of Medicine. It is humane, thought-provoking, and aims to instill in readers an understanding of the role of medicine in society and the contribution it can make to the health of populations, and it does not shy away from discussion of controversial aspects of modern medicine.
As always, there is detailed coverage of all areas of internal medicine by the world’s very best authors. The Oxford Textbook of Medicine seeks to embody advances in understanding and practice that have arisen through scientific research. The integration of basic science and clinical practice is unparalleled, and throughout the book the implications of research for medical practice are explained. The core clinical medicine sections offer in-depth coverage of the traditional specialty areas. The Oxford Textbook of Medicine has unsurpassed detail on infectious diseases: the most comprehensive coverage to be found in any textbook of medicine. Other sections of note include stem cells and regenerative medicine; inequalities in health; medical aspects of pollution and climate change; travel and expedition medicine; bioterrorism and forensic medicine; pain; medical disorders in pregnancy; nutrition; and psychiatry and drug related problems in general medical practice. The section on acute medicine is designed to give rapid access to information when it is needed quickly.
In response to ongoing user feedback there have been substantial changes to ensure that the Oxford Textbook of Medicine continues to meet the needs of its readers. Chapter essentials give accessible overviews of the content and a new design ensures that the textbook is easy to read and navigate. The evidence-base and references continue to be at the forefront of research.
New to this edition is that purchasers of the print version of the Oxford Textbook of Medicine sixth edition will have free access on Oxford Medicine Online to all the content plus regular updates for the life of the edition.
Table of Contents:
cover
Oxford Textbook of Medicine
Copyright
Foreword
Preface
Section editors
Contents
List of abbreviations xxxv
List of contributors xlv
SECTION 1 Patients and their treatment
1.1 On being a patient 3
1.2 A young person’s experience of chronic disease 6
1.3 What patients wish you understood 8
1.4 Why do patients attend and what do they want from the consultation? 14
1.5 Medical ethics 20 Mike Parker, Mehrunisha Suleman, and Tony Hope
1.6 Clinical decision- making 26 Timothy E.A. Peto and Philippa Peto
SECTION 2 Background to medicine
2.1 Science in medicine: When, how, and what 33
2.2 Evolution: Medicine’s most basic science 39
2.3 The Global Burden of Disease: Measuring the health of populations 43
2.4 Large- scale randomized evidence: Trials and meta- analyses of trials 51
2.5 Bioinformatics 67
2.6 Principles of clinical pharmacology and drug therapy 71
2.7 Biological therapies for immune, inflammatory, and allergic diseases 100
2.8 Traditional medicine exemplified by traditional Chinese medicine 108
2.9 Engaging patients in therapeutic development 118
2.10 Medicine quality, physicians, and patients 124
2.11 Preventive medicine 127
2.12 Medical screening 137
2.13 Health promotion 152
2.14 Deprivation and health 157
2.15 How much should rich countries’ governments spend on healthcare? 161
2.16 Financing healthcare in low- income developing countries: A challenge for equity in health 168
2.18 Fostering medical and health research in resource- constrained countries 181
2.17 Research in the developed world 177
2.19 Regulation versus innovation in medicine 185
2.20 Human disasters 188
2.21 Humanitarian medicine 193
2.22 Complementary and alternative medicine 201
SECTION 3 Cell biology
3.1 The cell 209
3.2 The genomic basis of medicine 218
3.3 Cytokines 236
3.4 Ion channels and disease 246
3.5 Intracellular signalling 256
3.6 Apoptosis in health and disease 266
3.7 Stem cells and regenerative medicine 281
3.8 The evolution of therapeutic antibodies 296
3.9 Circulating DNA for molecular diagnostics 299
SECTION 4 Immunological mechanisms
4.1 The innate immune system 307
4.2 The complement system 315
4.3 Adaptive immunity 325
4.4 Immunodeficiency 337
4.5 Allergy 368
4.6 Autoimmunity 379
4.7 Principles of transplantation immunology 392
SECTION 5 Principles of clinical oncology
5.1 Epidemiology of cancer 411
5.2 The nature and development of cancer: Cancer mutations and their implications 445
5.3 The genetics of inherited cancers 456
5.4 Cancer immunity and immunotherapy 471
5.5 Clinical features and management 487
5.6 Systemic treatment and radiotherapy 497
5.7 Medical management of breast cancer 505
SECTION 6 Old age medicine
6.1 Ageing and clinical medicine 511
6.2 Frailty and sarcopenia 521
6.3 Optimizing well- being into old age 532
6.4 Older people and urgent care 539
6.5 Older people in hospital 548
6.6 Supporting older peoples’ care in surgical and oncological services 563
6.7 Drugs and prescribing in the older patient 571
6.8 Falls, faints, and fragility fractures 579
6.9 Bladder and bowels 589
6.10 Neurodegenerative disorders in older people 601
6.11 Promotion of dignity in the life and death of older patients 612
SECTION 7 Pain and palliative care
7.1 Introduction to palliative care 623
7.2 Pain management 629
7.3 Symptoms other than pain 634
7.4 Care of the dying person 639
SECTION 8 Infectious diseases
8.1 Pathogenic microorganisms and the host 651
8.1.1 Biology of pathogenic microorganisms 651
8.1.2 Clinical features and general management of patients with severe infections 656
8.2 The patient with suspected infection 662
8.2.1 Clinical approach 662
8.2.2 Fever of unknown origin 664
8.2.3 Nosocomial infections 669
8.2.4 Infection in the immunocompromised host 673
8.2.5 Antimicrobial chemotherapy 684
8.3 Immunization 706
8.4 Travel and expedition medicine 713
8.5 Viruses 723
8.5.1 Respiratory tract viruses 723
8.5.2 Herpesviruses (excluding Epstein– Barr virus) 734
8.5.3 Epstein– Barr virus 754
8.5.4 Poxviruses 764
8.5.5 Mumps: Epidemic parotitis 769
8.5.6 Measles 772
8.5.7 Nipah and Hendra virus encephalitides 784
8.5.8 Enterovirus infections 787
8.5.9 Virus infections causing diarrhoea and vomiting 797
8.5.10 Rhabdoviruses: Rabies and rabies- related lyssaviruses 805
8.5.11 Colorado tick fever and other arthropod- borne reoviruses 819
8.5.12 Alphaviruses 821
8.5.13 Rubella 827
8.5.14 Flaviviruses excluding dengue 830
8.5.15 Dengue 845
8.5.16 Bunyaviridae 852
8.5.17 Arenaviruses 862
8.5.18 Filoviruses 870
8.5.19 Papillomaviruses and polyomaviruses 877
8.5.20 Parvovirus B19 886
8.5.21 Hepatitis viruses (excluding hepatitis C virus) 889
8.5.22 Hepatitis C virus 896
8.5.23 HIV/ AIDS 901
8.5.24 HIV in low- and middle- income countries 933
8.5.25 HTLV- 1, HTLV- 2, and associated diseases 941
8.5.26 Viruses and cancer 945
8.5.27 Orf and Milker’s nodule 947
8.5.28 Molluscum contagiosum 949
8.5.29 Newly discovered viruses 951
8.6 Bacteria 958
8.6.1 Diphtheria 959
8.6.2 Streptococci and enterococci 965
8.6.3 Pneumococcal infections 975
8.6.4 Staphylococci 991
8.6.5 Meningococcal infections 1010
8.6.6 Neisseria gonorrhoeae 1025
8.6.7 Enterobacteria and bacterial food poisoning 1032
8.6.8 Pseudomonas aeruginosa 1041
8.6.9 Typhoid and paratyphoid fevers 1044
8.6.10 Intracellular klebsiella infections (donovanosis and rhinoscleroma) 1051
8.6.11 Anaerobic bacteria 1055
8.6.12 Cholera 1060
8.6.13 Haemophilus influenzae 1066
8.6.14 Haemophilus ducreyi and chancroid 1071
8.6.15 Bordetella infection 1073
8.6.16 Melioidosis and glanders 1076
8.6.17 Plague: Yersinia pestis 1081
8.6.18 Other Yersinia infections: Yersiniosis 1086
8.6.19 Pasteurella 1088
8.6.20 Francisella tularensis infection 1091
8.6.21 Anthrax 1094
8.6.22 Brucellosis 1102
8.6.23 Tetanus 1109
8.6.24 Clostridium difficile 1115
8.6.25 Botulism, gas gangrene, and clostridial gastrointestinal infections 1120
8.6.26 Tuberculosis 1126
8.6.27 Disease caused by environmental mycobacteria 1150
8.6.28 Leprosy (Hansen’s disease) 1154
8.6.29 Buruli ulcer: Mycobacterium ulcerans infection 1167
8.6.30 Actinomycoses 1170
8.6.31 Nocardiosis 1176
8.6.32 Rat bite fevers (Streptobacillus moniliformis and Spirillum minus infection) 1179
8.6.33 Lyme borreliosis 1181
8.6.34 Relapsing fevers 1188
8.6.35 Leptospirosis 1198
8.6.36 Nonvenereal endemic treponematoses: Yaws, endemic syphilis (bejel), and pinta 1204
8.6.37 Syphilis 1210
8.6.38 Listeriosis 1223
8.6.39 Legionellosis and Legionnaires’ disease 1226
8.6.40 Rickettsioses 1230
8.6.41 Scrub typhus 1252
8.6.42 Coxiella burnetii infections (Q fever) 1257
8.6.43 Bartonellas excluding B. bacilliformis 1262
8.6.44 Bartonella bacilliformis infection 1272
8.6.45 Chlamydial infections 1278
8.6.46 Mycoplasmas 1295
8.6.47 A checklist of bacteria associated with infection in humans 1307
8.7 Fungi (mycoses) 1338
8.7.1 Fungal infections 1338
8.7.2 Cryptococcosis 1359
8.7.3 Coccidioidomycosis 1361
8.7.4 Paracoccidioidomycosis 1364
8.7.5 Pneumocystis jirovecii 1371
8.7.6 Talaromyces (Penicillium) marneffei infection 1375
8.7.7 Microsporidiosis 1378
8.8 Protozoa 1384
8.8.1 Amoebic infections 1384
8.8.2 Malaria 1395
8.8.3 Babesiosis 1414
8.8.4 Toxoplasmosis 1416
8.8.5 Cryptosporidium and cryptosporidiosis 1424
8.8.6 Cyclospora and cyclosporiasis 1432
8.8.7 Cystoisosporiasis 1436
8.8.9 Giardiasis and balantidiasis 1440
8.8.8 Sarcocystosis (sarcosporidiosis) 1438
8.8.10 Blastocystis infection 1449
8.8.11 Human African trypanosomiasis 1451
8.8.12 Chagas disease 1459
8.8.13 Leishmaniasis 1467
8.8.14 Trichomoniasis 1475
8.9 Nematodes (roundworms) 1478
8.9.1 Cutaneous filariasis 1478
8.9.2 Lymphatic filariasis 1487
8.9.3 Guinea worm disease (dracunculiasis) 1495
8.9.4 Strongyloidiasis, hookworm, and other gut strongyloid nematodes 1500
8.9.5 Gut and tissue nematode infections acquired by ingestion 1506
8.9.6 Angiostrongyliasis 1516
8.10 Cestodes (tapeworms) 1520
8.10.1 Cestodes (tapeworms) 1520
8.10.2 Cystic hydatid disease (Echinococcus granulosus) 1529
8.10.3 Cysticercosis 1533
8.11 Trematodes (flukes) 1540
8.11.1 Schistosomiasis 1540
8.11.2 Liver fluke infections 1551
8.11.3 Lung flukes (paragonimiasis) 1558
8.11.4 Intestinal trematode infections 1562
8.12 Nonvenomous arthropods 1568
8.13 Pentastomiasis (porocephalosis, linguatulosis/ linguatuliasis, or tongue worm infection) 1582
SECTION 9 Sexually transmitted diseases
9.1 Epidemiology of sexually transmitted infections 1589
9.2 Sexual behaviour 1597
9.3 Sexual history and examination 1600
9.4 Vaginal discharge 1603
9.5 Urethritis 1606
9.6 Genital ulceration 1610
9.7 Anogenital lumps and bumps 1613
9.8 Pelvic inflammatory disease 1622
9.9 Principles of contraception 1626
Index
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Also Download Other Volumes:
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